Nancy Cartwright
Bart Simson / Maggie Simpson / Nelson Muntz / Ralph Wiggum / The Happy Little Elves (voice)

Dan Castellaneta
Homer Simpson / Krusty the Clown / Grampa Simpson / Groundskeeper Willie / Squeaky Voiced Teen / Hans Moleman / Barney Gumble / Kodos / Repo Man / Mr. Freidman (voice)

Julie Kavner
Marge Simpson / Patty Bouvier / Selma Bouvier (voice)

Yeardley Smith
Lisa Simpson (voice)

Hank Azaria
Chief Wiggum / Apu Nahasapeemapetilon / Moe Szyslak / Professor Frink / Cletus Spuckler / Officer Lou / The Sarcastic Man / Snake Jailbird / Pants-off Johnson (voice)

Kelsey Grammer
Sideshow Bob (voice)

Pamela Hayden
Milhouse Van Houten (voice)

Russi Taylor
Martin Prince (voice)

Christopher Lloyd
Dr. Emmett L. Brown (voice)